SCHEMBL21563496

SCHEMBL21563496

Fc1c(F)c(N(c2ccc(-c3ccccc3)cc2)c2ccc(-c3ccccc3)cc2)c2nsnc2c1-c1ccc(-n2c3ccccc3c3ccccc32)cc1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HDAC4 P56524 1/20 0.32
KMT2A Q03164 1/20 0.32
MAPK14 Q16539 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21563624 0.82 KDM4E (0.35) KDM4EATML3MBTL1HDAC4KMT2A
SCHEMBL21563497 0.78 KDM4E (0.38) KDM4EATML3MBTL1HDAC4KMT2A
SCHEMBL22891387 0.78 KDM4E (0.37) KDM4EATML3MBTL1HDAC4KMT2A
SCHEMBL22891227 0.78 KDM4E (0.39) KDM4EATML3MBTL1HDAC4
SCHEMBL13726086 0.77 L3MBTL1 (0.41) KDM4EATML3MBTL1HDAC4KMT2A
SCHEMBL13725288 0.77 KDM4E (0.35) KDM4EATML3MBTL1HDAC4KMT2A
SCHEMBL12596161 0.76 KDM4E (0.47) KDM4EATML3MBTL1HDAC4KMT2A
SCHEMBL14000368 0.76 KDM4E (0.37) KDM4EATML3MBTL1HDAC4KMT2A
SCHEMBL12596186 0.76 L3MBTL1 (0.53) KDM4EATML3MBTL1HDAC4KMT2A
SCHEMBL12596165 0.75 L3MBTL1 (0.46) KDM4EATML3MBTL1HDAC4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10954227-B2 Nitrogen-containing cyclic compound and color conversion film comprising same LG CHEM, LTD. (KR) 2021-03-23 US disclosed
US-20200299290-A1 NITROGEN-CONTAINING CYCLIC COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME LG CHEM, LTD. (KR) 2020-09-24 US disclosed
WO-2019216573-A1 NITROGEN-CONTAINING CYCLIC COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME 주식회사 엘지화학 (KR) 2019-11-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200299290-A1 NITROGEN-CONTAINING CYCLIC COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME CRY1, NUDC, BLVRB KDM4E 1181/4885ATM 2510/4885L3MBTL1 2270/4885
US-10954227-B2 Nitrogen-containing cyclic compound and color conversion film comprising same CRY1, NUDC, BLVRB KDM4E 1181/4885ATM 2510/4885L3MBTL1 2270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.