Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 11/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29890836 | 0.92 | FURIN (0.51) | FURINGPR119 | |
| SCHEMBL21551214 | 0.92 | FURIN (0.51) | FURINGPR119 | |
| SCHEMBL30931804 | 0.92 | FURIN (0.51) | FURINGPR119 | |
| SCHEMBL21564423 | 0.92 | FURIN (0.55) | FURINGPR119 | |
| SCHEMBL29891173 | 0.91 | GPR119 (0.47) | FURINGPR119 | |
| SCHEMBL28547973 | 0.91 | GPR119 (0.47) | FURINGPR119 | |
| SCHEMBL21564372 | 0.89 | GPR119 (0.49) | FURINGPR119 | |
| SCHEMBL30931850 | 0.87 | GPR119 (0.45) | FURINGPR119 | |
| SCHEMBL21551237 | 0.87 | GPR119 (0.45) | FURINGPR119 | |
| SCHEMBL29890911 | 0.87 | GPR119 (0.45) | FURINGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019215341-A1 | FURIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-11-14 | — | — | WO | disclosed |
| US-9388132-B2 | Isobaric tandem mass tags for quantitative proteomics and peptidomics | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2016-07-12 | — | — | US | disclosed |