Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.47 |
| ▸ | FURIN | P09958 | 11/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29891173 | 1.00 | GPR119 (0.47) | GPR119FURIN | |
| SCHEMBL29891051 | 0.95 | FURIN (0.52) | GPR119FURIN | |
| SCHEMBL21551750 | 0.95 | FURIN (0.52) | GPR119FURIN | |
| SCHEMBL21551403 | 0.92 | FURIN (0.52) | GPR119FURIN | |
| SCHEMBL29890774 | 0.92 | FURIN (0.52) | GPR119FURIN | |
| SCHEMBL21564353 | 0.91 | FURIN (0.49) | GPR119FURIN | |
| SCHEMBL21551196 | 0.91 | GPR119 (0.50) | GPR119FURIN | |
| SCHEMBL29890640 | 0.91 | GPR119 (0.50) | GPR119FURIN | |
| SCHEMBL21551306 | 0.90 | FURIN (0.52) | FURIN | |
| SCHEMBL21551214 | 0.90 | FURIN (0.51) | GPR119FURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384509-B | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-112384509-A | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-02-19 | — | — | CN | disclosed |