Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.47 |
| ▸ | FURIN | P09958 | 6/20 | 0.42 |
| ▸ | RET | P07949 | 4/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 2/20 | 0.41 |
| ▸ | SKP1 | P63208 | 2/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.41 |
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29891921 | 0.93 | GPR119 (0.46) | GPR119FURINRETWNT3ACKS1B | |
| SCHEMBL30931821 | 0.93 | GPR119 (0.46) | GPR119FURINRETWNT3ACKS1B | |
| SCHEMBL21551253 | 0.93 | GPR119 (0.46) | GPR119FURINRETWNT3ACKS1B | |
| SCHEMBL28546917 | 0.92 | GPR119 (0.50) | GPR119FURINRETWNT3ACKS1B | |
| SCHEMBL29890665 | 0.92 | GPR119 (0.50) | GPR119FURINRETWNT3ACKS1B | |
| SCHEMBL21551516 | 0.87 | GPR119 (0.42) | GPR119FURINRETWNT3ACKS1B | |
| SCHEMBL30931835 | 0.87 | GPR119 (0.42) | GPR119FURINRETWNT3ACKS1B | |
| SCHEMBL29890753 | 0.87 | GPR119 (0.42) | GPR119FURINRETWNT3ACKS1B | |
| SCHEMBL21551594 | 0.87 | CKS1B (0.44) | GPR119FURINRETWNT3ACKS1B | |
| SCHEMBL21564422 | 0.87 | FURIN (0.54) | GPR119FURINRETWNT3ACKS1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3790871-B1 | FURIN INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2024-01-24 | — | — | EP | disclosed |
| WO-2019215341-A1 | FURIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-11-14 | — | — | WO | disclosed |