Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 8/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21564542 | 0.90 | KDM1A (0.36) | KDM1AHTR1AGRIA1CHEK1AOC3 | |
| SCHEMBL21564544 | 0.88 | KDM1A (0.34) | NOTUMKDM1ATP53 | |
| SCHEMBL21564667 | 0.87 | ALDH1A1 (0.33) | KDM4E | |
| SCHEMBL21552894 | 0.85 | EP300 (0.40) | NOTUMKDM1AHTR1AKDM4EADORA2A | |
| SCHEMBL21564561 | 0.85 | TLR8 (0.40) | KDM4E | |
| SCHEMBL21564890 | 0.85 | ALDH1A1 (0.40) | NOTUMGRIA1CYP11B2KDM4E | |
| SCHEMBL26036663 | 0.83 | ALDH1A1 (0.35) | NOTUMKDM1AHTR1AGRIA1CYP11B2 | |
| SCHEMBL21552997 | 0.78 | EP300 (0.40) | NOTUMCYP11B2CYP11B1 | |
| SCHEMBL23258228 | 0.76 | KDM4E (0.37) | KDM1AHTR1AKDM4E | |
| SCHEMBL21564847 | 0.75 | SLC6A2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019217972-A1 | KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE | IMAGO BIOSCIENCES, INC. (US) | 2019-11-14 | — | — | WO | disclosed |