Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1443794 | 0.86 | POLB (0.61) | POLBLTA4H | |
| SCHEMBL18577442 | 0.86 | POLB (0.61) | POLBLTA4H | |
| SCHEMBL10132295 | 0.86 | POLB (0.61) | POLBLTA4H | |
| SCHEMBL18577477 | 0.85 | POLB (0.69) | POLBLTA4H | |
| Hydrochloric Acid SCHEMBL7278039 | 0.85 | POLB (0.59) | POLBLTA4H | |
| SCHEMBL18577474 | 0.85 | POLB (0.69) | POLBLTA4H | |
| SCHEMBL11474398 | 0.83 | POLB (0.67) | POLBLTA4H | |
| Hydrochloric Acid SCHEMBL7248436 | 0.83 | POLB (0.67) | POLBLTA4H | |
| Hydrochloric Acid SCHEMBL11472694 | 0.82 | POLB (0.65) | POLBLTA4H | |
| SCHEMBL7460081 | 0.81 | LTA4H (0.40) | POLBLTA4HALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190345137-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS | GALAPAGOS NV (BE) | 2019-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190345137-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS | CHIA, CHIT1, AADAC | POLB 3468/4885LTA4H 564/4885ALDH1A1 1830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.