Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24538689 | 0.92 | TLR7 (0.43) | TSPOKIF11TLR8TLR7TP53 | |
| SCHEMBL21566344 | 0.85 | TLR7 (0.54) | TLR8TLR7 | |
| SCHEMBL29920814 | 0.83 | TSPO (0.39) | TSPOLMNATBXA2RTLR7MEN1 | |
| SCHEMBL21949797 | 0.83 | TSPO (0.39) | TSPOLMNATBXA2RTLR7MEN1 | |
| SCHEMBL21550166 | 0.77 | TLR7 (0.43) | LMNATBXA2RERCC5FEN1KIF11 | |
| SCHEMBL29871760 | 0.77 | TLR7 (0.63) | TLR8TLR7 | |
| SCHEMBL24539662 | 0.77 | TLR7 (0.63) | TLR8TLR7 | |
| SCHEMBL24538536 | 0.76 | TLR7 (0.57) | TLR8TLR7 | |
| SCHEMBL30876988 | 0.76 | TLR7 (0.57) | TLR8TLR7 | |
| SCHEMBL21566342 | 0.75 | NLRP3 (0.47) | TSPOTLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019214546-A1 | FUSED RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 (CN) | 2019-11-14 | — | — | WO | disclosed |