Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 20/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21976791 | 0.86 | HDAC4 (0.61) | HDAC4HDAC6HDAC8 | |
| SCHEMBL21462401 | 0.81 | HDAC4 (0.68) | HDAC4HDAC6HDAC8 | |
| SCHEMBL20505610 | 0.79 | HDAC4 (0.67) | HDAC4HDAC6HDAC8 | |
| SCHEMBL21543823 | 0.78 | HDAC4 (0.69) | HDAC4HDAC6HDAC8 | |
| SCHEMBL14645583 | 0.77 | HDAC4 (1.00) | HDAC4HDAC6HDAC8 | |
| SCHEMBL19100146 | 0.77 | HDAC4 (0.61) | HDAC4HDAC6 | |
| SCHEMBL20482034 | 0.77 | HDAC4 (0.64) | HDAC4HDAC6HDAC8 | |
| SCHEMBL18609313 | 0.77 | HDAC4 (0.60) | HDAC4HDAC6HDAC8 | |
| SCHEMBL18824404 | 0.77 | HDAC4 (0.62) | HDAC4HDAC6HDAC8 | |
| SCHEMBL24040150 | 0.76 | HDAC4 (0.58) | HDAC4HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190345150-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190345150-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | PRF1, NOX1, ARG1 | HDAC4 1435/4885HDAC6 610/4885HDAC8 1766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.