SCHEMBL21462401

SCHEMBL21462401

CN(C)C(=O)Oc1ccc(-c2noc(C(F)(F)F)n2)cc1

nearest known ligand 0.68

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 20/20 0.68
HDAC6 Q9UBN7 8/20 0.62
HDAC8 Q9BY41 1/20 0.57
HDAC1 Q13547 2/20 0.55
HDAC3 O15379 1/20 0.54
HDAC7 Q8WUI4 1/20 0.54
HDAC2 Q92769 1/20 0.54
HDAC5 Q9UQL6 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19432805 0.88 HDAC4 (0.71) HDAC4HDAC6HDAC8HDAC1HDAC3
SCHEMBL20622460 0.84 HDAC4 (0.54) HDAC4HDAC6HDAC8HDAC1
SCHEMBL28702951 0.83 HDAC4 (0.58) HDAC4HDAC6HDAC8HDAC1HDAC2
SCHEMBL10697484 0.82 HDAC4 (0.68) HDAC4HDAC6HDAC8HDAC1HDAC5
SCHEMBL21543823 0.81 HDAC4 (0.69) HDAC4HDAC6HDAC8HDAC1HDAC3
SCHEMBL14645583 0.81 HDAC4 (1.00) HDAC4HDAC6HDAC8HDAC1HDAC3
SCHEMBL21567058 0.81 HDAC4 (0.62) HDAC4HDAC6HDAC8
SCHEMBL10552122 0.79 HDAC4 (0.70) HDAC4HDAC6HDAC8HDAC1HDAC3
SCHEMBL10558210 0.79 HDAC4 (0.74) HDAC4HDAC6HDAC8HDAC1HDAC5
SCHEMBL21175476 0.79 HDAC4 (0.76) HDAC4HDAC6HDAC8HDAC1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4384016-B1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE BAYER AG (DE) 2025-09-03 EP claimed
WO-2025098874-A1 ACTIVE COMPOUND COMBINATIONS HAVING FUNGICIDAL/INSECTICIDAL/ACARICIDAL PROPERTIES BAYER AKTIENGESELLSCHAFT (DE) 2025-05-15 WO claimed
US-20240365785-A1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE BAYER AKTIENGESELLSCHAFT (DE) 2024-11-07 US claimed
EP-4384016-A1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE Bayer Aktiengesellschaft (DE) 2024-06-19 EP claimed
CN-118102874-A Active compound combinations and fungicide compositions comprising them 拜耳公司 2024-05-28 CN claimed
US-20240016152-A1 ACTIVE COMPOUND COMBINATIONS BAYER AKTIENGESELLSCHAFT (DE) 2024-01-18 US claimed
US-20230165252-A1 ACTIVE COMPOUND COMBINATIONS BAYER AKTIENGESELLSCHAFT (DE) 2023-06-01 US claimed
EP-4167740-A1 ACTIVE COMPOUND COMBINATIONS Bayer Aktiengesellschaft (DE) 2023-04-26 EP claimed
EP-4156936-A1 ACTIVE COMPOUND COMBINATIONS Bayer Aktiengesellschaft (DE) 2023-04-05 EP claimed
WO-2023017120-A1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE BAYER AKTIENGESELLSCHAFT (DE) 2023-02-16 WO claimed
WO-2021255070-A1 ACTIVE COMPOUND COMBINATIONS BAYER AKTIENGESELLSCHAFT (DE) 2021-12-23 WO claimed
WO-2021239766-A1 ACTIVE COMPOUND COMBINATIONS BAYER AKTIENGESELLSCHAFT (DE) 2021-12-02 WO claimed
EP-4536001-B1 AGROCHEMICAL FORMULATIONS COMPRISING CRYSTALLINE FORM A OF 4-[(6-CHLORO-3-PYRIDYLMETHYL)(2,2-DIFLUOROETHYL)AMINO]FURAN-2(5H)-ONE BAYER AG (DE) 2026-03-11 EP disclosed
US-12552748-B2 Pyridine (thio)amides as fungicidal compounds BAYER AKTIENGESELLSCHAFT (DE) 2026-02-17 US disclosed
EP-4149929-B1 TRIAZINE AND PYRIMIDINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS BAYER AG (DE) 2026-01-28 EP disclosed
EP-3986138-B1 A BACILLUS STRAIN AND METHODS OF ITS USE FOR PLANT GROWTH PROMOTION UNIV AUBURN (US) 2026-01-28 EP disclosed
WO-2020254487-A1 HYDROXYISOXAZOLINES AND DERIVATIVES THEREOF BAYER AKTIENGESELLSCHAFT (DE) 2020-12-24 WO disclosed
EP-3708565-A1 PYRIMIDINYLOXYPHENYLAMIDINES AND THE USE THEREOF AS FUNGICIDES Bayer AG (DE) 2020-09-16 EP disclosed
WO-2019197371-A1 OXADIAZOLINE DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2019-10-17 WO disclosed
WO-2019197371-A1 OXADIAZOLINE DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2019-10-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240016152-A1 ACTIVE COMPOUND COMBINATIONS CYP51A1, ERG28, BROX HDAC4 748/4885HDAC6 624/4885HDAC8 571/4885
US-20230165252-A1 ACTIVE COMPOUND COMBINATIONS CYP51A1, ERG28, BROX HDAC4 748/4885HDAC6 624/4885HDAC8 571/4885
US-20240365785-A1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE DDT, TH, HPD HDAC4 180/4885HDAC6 1188/4885HDAC8 424/4885
US-12552748-B2 Pyridine (thio)amides as fungicidal compounds CBR1, CBR3, TH HDAC4 1039/4885HDAC6 788/4885HDAC8 761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.