Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 12/20 | 1.00 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.64 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.60 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.60 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.60 |
| ▸ | GSK3B | P49841 | 1/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.58 |
| ▸ | LDHA | P00338 | 1/20 | 0.56 |
| ▸ | STAT1 | P42224 | 1/20 | 0.55 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21568049 | 0.86 | DYRK1A (0.76) | DYRK1APIK3CGNPC1RAB9ACYP1A2 | |
| SCHEMBL6067966 | 0.86 | DYRK1A (0.76) | DYRK1APIK3CGNPC1RAB9ACYP1A2 | |
| SCHEMBL13718453 | 0.85 | DYRK1A (0.74) | DYRK1APIK3CGNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6068126 | 0.83 | DYRK1A (0.71) | DYRK1APIK3CGNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6067971 | 0.82 | DYRK1A (0.69) | DYRK1APIK3CGNPC1RAB9ACYP1A2 | |
| SCHEMBL23256895 | 0.81 | DYRK1A (0.68) | DYRK1ANPC1RAB9ASMN1; SMN2GSK3B | |
| SCHEMBL23256870 | 0.81 | DYRK1A (0.70) | DYRK1ANPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL21568954 | 0.80 | DYRK1A (0.66) | DYRK1APIK3CGNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3409205 | 0.80 | DYRK1A (0.67) | DYRK1APIK3CGNPC1RAB9ACYP1A2 | |
| SCHEMBL23256883 | 0.80 | DYRK1A (0.66) | DYRK1ANPC1RAB9ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019217509-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | HB THERAPEUTICS INC. (US) | 2019-11-14 | — | — | WO | disclosed |