Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2156350 | 0.89 | ALDH1A1 (0.41) | GAAKMT2AMEN1MAPTLMNA | |
| SCHEMBL1319262 | 0.77 | GAA (0.42) | GAAPKMNR3C1CYP2C19 | |
| SCHEMBL82964 | 0.76 | GAA (0.42) | GAAPKMNR3C1CYP2C19 | |
| SCHEMBL28753759 | 0.74 | ALDH1A1 (0.33) | KMT2AMEN1ELANEMAPT | |
| SCHEMBL9467353 | 0.69 | BCHE (0.41) | GAAKMT2ALMNAHTTNR3C1 | |
| SCHEMBL28310610 | 0.69 | KMT2A (0.43) | GAAPKMKMT2AMEN1LMNA | |
| SCHEMBL5535445 | 0.69 | STAT3 (0.40) | GAAKMT2AELANELMNAHTT | |
| SCHEMBL3807712 | 0.69 | STAT3 (0.40) | GAAKMT2AELANELMNAHTT | |
| SCHEMBL3807715 | 0.69 | STAT3 (0.40) | GAAKMT2AELANELMNAHTT | |
| SCHEMBL2156927 | 0.67 | ELANE (0.44) | ELANEMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973026-B2 | Thienopyrroles as antiviral agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2011-07-05 | — | — | US | disclosed |