Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2156930 | 0.89 | GAA (0.39) | KMT2ANR3C1HTTGAAMAPT | |
| SCHEMBL2156736 | 0.75 | OPRM1 (0.36) | ALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL28753759 | 0.72 | ALDH1A1 (0.33) | ALDH1A1KMT2AMAPTMEN1SMN1; SMN2 | |
| SCHEMBL59929 | 0.71 | ALDH1A1 (0.43) | ALDH1A1KMT2AHSP90AA1MMP2 | |
| SCHEMBL12433575 | 0.71 | ALDH1A1 (0.43) | ALDH1A1KMT2AHSP90AA1MMP2 | |
| SCHEMBL58248 | 0.71 | ALDH1A1 (0.43) | ALDH1A1KMT2AHSP90AA1MMP2 | |
| SCHEMBL2156340 | 0.69 | TDP1 (0.41) | ALDH1A1KMT2AHSP90AA1L3MBTL1CYP2C9 | |
| SCHEMBL27724423 | 0.68 | HTT (0.55) | ALDH1A1KMT2AHSP90AA1NR3C1L3MBTL1 | |
| SCHEMBL4387114 | 0.68 | PRMT5 (0.42) | ALDH1A1KMT2AHSP90AA1MMP2 | |
| SCHEMBL394197 | 0.67 | ALDH1A1 (0.39) | ALDH1A1KMT2AHSP90AA1FAAHHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973026-B2 | Thienopyrroles as antiviral agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2011-07-05 | — | — | US | disclosed |