Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 11/20 | 0.46 |
| ▸ | SLC5A2 | P31639 | 8/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SLC28A3 | Q9HAS3 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3396798 | 0.83 | MAOB (0.45) | MAPTHPGDMEN1KMT2AKDM4E | |
| SCHEMBL2023335 | 0.79 | MEN1 (0.47) | CYP19A1MAPTHPGDHSD17B10NFKB1 | |
| SCHEMBL2020902 | 0.78 | SLC5A1 (0.43) | SLC5A1SLC5A2CYP19A1MAPTHSD17B10 | |
| SCHEMBL2023203 | 0.73 | AURKA (0.40) | SLC5A1SLC5A2CYP19A1NFKB1NFKB2 | |
| SCHEMBL15313125 | 0.73 | ALDH1A1 (0.45) | KDM4EALDH1A1POLBACHE | |
| SCHEMBL2024880 | 0.72 | CAPN1 (0.44) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| Phloretin SCHEMBL21192491 | 0.70 | SLC5A1 (0.87) | SLC5A1SLC5A2CYP19A1MAPTSLC28A3 | |
| Phloretin SCHEMBL1260339 | 0.69 | SLC5A1 (0.51) | SLC5A1SLC5A2CYP19A1MAPTSLC28A3 | |
| SCHEMBL31527864 | 0.69 | MAOB (0.45) | MAPTHPGDMEN1KMT2AKDM4E | |
| SCHEMBL27182973 | 0.69 | MAOB (0.45) | MAPTHPGDMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9198451-B2 | Aroma composition to reduce or suppress undesirable bitter and astringent taste impressions of sweeteners | SYMRISE AG (DE) | 2015-12-01 | — | — | US | disclosed |
| EP-2340719-B1 | Aroma composition comprising o-coumaric acid to reduce or suppress undesirable taste impressions of sweeteners | SYMRISE AG (DE) | 2014-02-19 | — | — | EP | disclosed |
| EP-2220945-B1 | Aroma composition to reduce or suppress undesirable bitter and astringent taste impressions of sweeteners | SYMRISE AG (DE) | 2013-03-27 | — | — | EP | disclosed |
| EP-2340719-A1 | Aroma composition comprising o-coumaric acid to reduce or suppress undesirable taste impressions of sweeteners | Symrise AG (DE) | 2011-07-06 | — | — | EP | disclosed |
| EP-2220945-A1 | Aroma composition to reduce or suppress undesirable bitter and astringent taste impressions of sweeteners | Symrise GmbH & Co. KG (DE) | 2010-08-25 | — | — | EP | disclosed |
| US-20100151055-A1 | Aroma Composition to Reduce or Suppress Undesirable Bitter and Astringent Taste Impressions of Sweeteners | SYMRISE GMBH & CO. KG (DE) | 2010-06-17 | — | — | US | disclosed |