Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.39 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | ULK1 | O75385 | 1/20 | 0.39 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21571868 | 0.86 | SLC22A12 (0.42) | SLC22A12CYP11B1CYP11B2MKNK2ROCK2 | |
| SCHEMBL8312695 | 0.78 | ALDH1A1 (0.46) | SLC22A12CYP11B1CYP11B2MKNK2ROCK2 | |
| SCHEMBL12403827 | 0.77 | ALDH1A1 (0.52) | CYP1A2CYP3A4CYP2C9CYP1A1CYP1B1 | |
| SCHEMBL22421831 | 0.77 | DYRK1A (0.42) | SLC22A12CYP11B1CYP11B2MKNK2ROCK2 | |
| SCHEMBL22421832 | 0.76 | CYP11B1 (0.44) | SLC22A12CYP11B1CYP11B2MKNK2ROCK2 | |
| SCHEMBL26328401 | 0.76 | SLC22A12 (0.41) | SLC22A12CYP11B1CYP11B2MKNK2ROCK2 | |
| SCHEMBL25145152 | 0.75 | PDK1 (0.51) | SLC22A12DYRK1ACYP1A2CYP2C9SCN10A | |
| Hydrochloric Acid SCHEMBL29418006 | 0.74 | SLC22A12 (0.40) | SLC22A12CYP11B1CYP11B2MKNK2ROCK2 | |
| Hydrochloric Acid SCHEMBL25239818 | 0.74 | SLC22A12 (0.40) | SLC22A12CYP11B1CYP11B2MKNK2ROCK2 | |
| SCHEMBL23148020 | 0.74 | NPC1 (0.50) | SLC22A12MKNK2SCN10AALDH1A1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10479793-B2 | Imidazopyridazine compounds useful as modulators of IL-12, IL-23 and/or IFN alpha responses | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10479793-B2 | Imidazopyridazine compounds useful as modulators of IL-12, IL-23 and/or IFN alpha responses | TYK2, IL2, JAK3 | SLC22A12 3315/4885CYP11B1 848/4885CYP11B2 445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.