Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | S100A4 | P26447 | 5/20 | 1.00 |
| ▸ | PTPRC | P08575 | 5/20 | 1.00 |
| ▸ | APAF1 | O14727 | 4/20 | 1.00 |
| ▸ | TDP2 | O95551 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | RAB9A | P51151 | 4/20 | 1.00 |
| ▸ | BLM | P54132 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | NPC1 | O15118 | 3/20 | 1.00 |
| ▸ | HTT | P42858 | 3/20 | 1.00 |
| ▸ | GALK1 | P51570 | 3/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 1.00 |
| ▸ | PLA2G1B | P04054 | 3/20 | 1.00 |
| ▸ | ATG4B | Q9Y4P1 | 3/20 | 1.00 |
| ▸ | PLCG1 | P19174 | 2/20 | 1.00 |
| ▸ | PPARG | P37231 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 9,10-Phenanthrenequinone SCHEMBL31598775 | 1.00 | MEN1 (1.00) | MEN1KMT2AS100A4PTPRCAPAF1 | |
| 9,10-Phenanthrenequinone SCHEMBL43050 | 1.00 | MEN1 (1.00) | MEN1KMT2AS100A4PTPRCAPAF1 | |
| 9,10-Phenanthrenequinone SCHEMBL29384320 | 1.00 | MEN1 (1.00) | MEN1KMT2AS100A4PTPRCAPAF1 | |
| 9,10-Phenanthrenequinone SCHEMBL28585734 | 0.96 | S100A4 (0.93) | MEN1KMT2AS100A4PTPRCAPAF1 | |
| 9,10-Phenanthrenequinone SCHEMBL29548993 | 0.96 | S100A4 (0.93) | MEN1KMT2AS100A4PTPRCAPAF1 | |
| 9,10-Phenanthrenequinone SCHEMBL17536499 | 0.96 | S100A4 (0.93) | MEN1KMT2AS100A4PTPRCAPAF1 | |
| 9,10-Phenanthrenequinone SCHEMBL11634370 | 0.96 | S100A4 (0.93) | MEN1KMT2AS100A4PTPRCAPAF1 | |
| 9,10-Phenanthrenequinone SCHEMBL29746976 | 0.96 | S100A4 (0.93) | MEN1KMT2AS100A4PTPRCAPAF1 | |
| 9,10-Phenanthrenequinone SCHEMBL29548092 | 0.96 | S100A4 (0.93) | MEN1KMT2AS100A4PTPRCAPAF1 | |
| 9,10-Phenanthrenequinone SCHEMBL28594289 | 0.96 | S100A4 (0.93) | MEN1KMT2AS100A4PTPRCAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973034-B2 | Ameliorating toxic effects of such as cancer therapy drugs or addictive drug overdose | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2011-07-05 | — | — | US | disclosed |
| US-20050054691-A1 | Carboxylesterase inhibitors | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2005-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050054691-A1 | Carboxylesterase inhibitors | CES1, CES2, BCHE | MEN1 4615/4885KMT2A 1241/4885S100A4 4674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.