Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 5/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21572530 | 0.96 | KMT2A (0.40) | KMT2AMEN1ALDH1A1SMN1; SMN2MMP2 | |
| SCHEMBL21572202 | 0.84 | MMP2 (0.38) | KMT2AMEN1ALDH1A1MMP2MMP13 | |
| SCHEMBL18332094 | 0.82 | KMT2A (0.39) | KMT2AMEN1ALDH1A1SMN1; SMN2MMP2 | |
| SCHEMBL20084843 | 0.81 | MEN1 (0.38) | KMT2AMEN1ALDH1A1MMP13RXFP1 | |
| SCHEMBL18332092 | 0.81 | MEN1 (0.40) | KMT2AMEN1ALDH1A1SMN1; SMN2MMP2 | |
| SCHEMBL21572135 | 0.78 | KMT2A (0.39) | KMT2AMEN1ALDH1A1SMN1; SMN2MMP2 | |
| SCHEMBL18332517 | 0.78 | KMT2A (0.39) | KMT2AMEN1ALDH1A1SMN1; SMN2MMP2 | |
| SCHEMBL20084046 | 0.78 | GRIN2D (0.41) | KMT2AMEN1RXFP1SRD5A1SRD5A2 | |
| SCHEMBL16402131 | 0.77 | SRD5A1 (0.50) | KMT2AMEN1ALDH1A1SMN1; SMN2MMP2 | |
| SCHEMBL18332088 | 0.77 | MMP13 (0.63) | KMT2AMEN1ALDH1A1SMN1; SMN2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10479780-B2 | Aminopyrazole derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2019-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10479780-B2 | Aminopyrazole derivatives | SRC, GRK2, GRK3 | KMT2A 1100/4885MEN1 3006/4885ALDH1A1 1534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.