Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18332182 | 0.86 | ALDH1A1 (0.44) | LMNASMN1; SMN2ALDH1A1GAASLC6A4 | |
| SCHEMBL18331729 | 0.81 | XIAP (0.38) | ARXIAPKCNH2SLC6A2SLC6A4 | |
| SCHEMBL21572218 | 0.80 | TRPA1 (0.39) | ALDH1A1GAASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18956930 | 0.79 | MEN1 (0.44) | SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL14396816 | 0.74 | SLC6A4 (0.55) | ARXIAPKCNH2SLC6A2SLC6A4 | |
| SCHEMBL18332252 | 0.73 | PARP10 (0.50) | SMN1; SMN2ALDH1A1GAASLC6A2SLC6A4 | |
| SCHEMBL16792647 | 0.73 | ALDH1A1 (0.42) | LMNAALDH1A1GAASLC6A2SLC6A4 | |
| SCHEMBL15955536 | 0.72 | PARP10 (0.46) | ARALDH1A1GAADPP4KCNH2 | |
| SCHEMBL9702388 | 0.72 | XIAP (0.45) | ARXIAPLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL754388 | 0.71 | XIAP (0.47) | ARXIAPLMNAALDH1A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10479780-B2 | Aminopyrazole derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2019-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10479780-B2 | Aminopyrazole derivatives | SRC, GRK2, GRK3 | AR 18/4885XIAP 2978/4885LMNA 4871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.