Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20085062 | 0.80 | HDAC1 (0.31) | HDAC1HDAC6CA1CA2CA9 | |
| SCHEMBL20084682 | 0.80 | HDAC1 (0.31) | HDAC1HDAC6CA1CA2CA9 | |
| SCHEMBL20085098 | 0.77 | — | — | |
| SCHEMBL20084487 | 0.76 | RAB9A (0.40) | — | |
| SCHEMBL20085013 | 0.75 | NPC1 (0.31) | — | |
| SCHEMBL21970727 | 0.75 | NOD1 (0.43) | CA1CA2CA9 | |
| SCHEMBL20084989 | 0.75 | HDAC1 (0.32) | HDAC1HDAC6CA1CA2CA9 | |
| SCHEMBL20084628 | 0.73 | HDAC1 (0.35) | HDAC1HDAC6CA1CA2CA9 | |
| SCHEMBL21970607 | 0.68 | HDAC1 (0.35) | HDAC1HDAC6CA1CA2CA9 | |
| SCHEMBL21572169 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10479780-B2 | Aminopyrazole derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2019-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10479780-B2 | Aminopyrazole derivatives | SRC, GRK2, GRK3 | HDAC1 396/4885HDAC6 480/4885CA1 4757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.