Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 19/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18933434 | 0.85 | EGFR (0.56) | EGFRERBB2SRCKDR | |
| SCHEMBL19223020 | 0.85 | EGFR (0.71) | EGFRERBB2 | |
| SCHEMBL21573295 | 0.84 | EGFR (0.55) | EGFRERBB2SRCKDR | |
| SCHEMBL18933474 | 0.81 | EGFR (0.64) | EGFRERBB2SRCKDR | |
| SCHEMBL18949445 | 0.81 | EGFR (0.64) | EGFRERBB2SRCKDR | |
| SCHEMBL19389827 | 0.81 | EGFR (0.64) | EGFRERBB2SRCKDR | |
| SCHEMBL21573261 | 0.81 | EGFR (0.58) | EGFRERBB2 | |
| SCHEMBL19223044 | 0.78 | EGFR (0.51) | EGFRERBB2 | |
| SCHEMBL18933435 | 0.77 | EGFR (0.50) | EGFRERBB2SRCKDR | |
| SCHEMBL19389768 | 0.76 | EGFR (0.53) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3222620-B1 | CYANOQUINOLINE DERIVATIVES | TIANJIN HEMAY ONCOLOGY PHARMACEUTICAL CO LTD (CN) | 2019-11-20 | — | — | EP | disclosed |