Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 16/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 13/20 | 0.50 |
| ▸ | GAK | O14976 | 2/20 | 0.49 |
| ▸ | STK4 | Q13043 | 1/20 | 0.48 |
| ▸ | RAF1 | P04049 | 1/20 | 0.47 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19389771 | 0.81 | EGFR (0.49) | EGFRERBB2GAKSTK4 | |
| SCHEMBL21573295 | 0.74 | EGFR (0.55) | SRCEGFRERBB2GAKSTK4 | |
| SCHEMBL18933435 | 0.73 | EGFR (0.50) | SRCEGFRERBB2GAKSTK4 | |
| SCHEMBL18933434 | 0.73 | EGFR (0.56) | SRCEGFRERBB2GAKSTK4 | |
| SCHEMBL6384074 | 0.72 | EGFR (0.74) | SRCEGFRERBB2GAKRAF1 | |
| SCHEMBL1898103 | 0.72 | EGFR (0.63) | EGFRERBB2GAKSTK4 | |
| SCHEMBL6381844 | 0.72 | EGFR (0.79) | EGFRERBB2STK4 | |
| SCHEMBL19223056 | 0.71 | EGFR (0.55) | SRCEGFRERBB2GAKSTK4 | |
| SCHEMBL18949482 | 0.71 | EGFR (0.60) | SRCEGFRERBB2GAKSTK4 | |
| SCHEMBL12094771 | 0.70 | EGFR (0.72) | SRCEGFRERBB2GAKRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3222620-B1 | CYANOQUINOLINE DERIVATIVES | TIANJIN HEMAY ONCOLOGY PHARMACEUTICAL CO LTD (CN) | 2019-11-20 | — | — | EP | disclosed |