Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 15/20 | 0.49 |
| ▸ | STK4 | Q13043 | 3/20 | 0.49 |
| ▸ | GAK | O14976 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18933465 | 0.85 | EGFR (0.64) | EGFRERBB2STK4GAK | |
| SCHEMBL18933435 | 0.82 | EGFR (0.50) | EGFRERBB2STK4GAK | |
| SCHEMBL21573295 | 0.81 | EGFR (0.55) | EGFRERBB2STK4GAK | |
| SCHEMBL21573318 | 0.81 | SRC (0.52) | EGFRERBB2STK4GAK | |
| SCHEMBL18933434 | 0.75 | EGFR (0.56) | EGFRERBB2STK4GAK | |
| SCHEMBL18949482 | 0.74 | EGFR (0.60) | EGFRERBB2STK4GAK | |
| SCHEMBL18949427 | 0.74 | EGFR (0.58) | EGFRERBB2STK4GAK | |
| SCHEMBL21573263 | 0.71 | EGFR (0.58) | EGFRERBB2STK4GAK | |
| SCHEMBL19223046 | 0.70 | EGFR (0.48) | EGFRERBB2STK4GAK | |
| SCHEMBL19223056 | 0.70 | EGFR (0.55) | EGFRERBB2STK4GAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3222620-A1 | CYANOQUINOLINE DERIVATIVES | TIANJIN HEMAY ONCOLOGY PHARMACEUTICAL CO., LTD. (CN) | 2017-09-27 | — | — | EP | disclosed |