Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.38 |
| ▸ | CTSL | P07711 | 13/20 | 0.37 |
| ▸ | CTSB | P07858 | 9/20 | 0.34 |
| ▸ | CTSS | P25774 | 9/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2156782 | 0.90 | CTSL (0.33) | CTSKCTSLCTSBCTSS | |
| SCHEMBL2156059 | 0.85 | CTSL (0.33) | CTSKCTSLCTSBCTSS | |
| SCHEMBL2157348 | 0.83 | CTSK (0.38) | CTSKCTSLCTSBCTSS | |
| SCHEMBL2156169 | 0.82 | CTSL (0.49) | CTSKCTSLCTSBCTSS | |
| SCHEMBL2155056 | 0.81 | CTSL (0.40) | CTSKCTSLCTSBCTSS | |
| SCHEMBL2155258 | 0.80 | CTSL (0.35) | CTSKCTSLCTSBCTSS | |
| SCHEMBL2156690 | 0.79 | CTSK (0.48) | CTSKCTSLCTSBCTSS | |
| SCHEMBL2157370 | 0.78 | CTSK (0.36) | CTSKCTSLCTSBCTSS | |
| SCHEMBL2155032 | 0.78 | CTSL (0.37) | CTSKCTSLCTSBCTSS | |
| SCHEMBL2156797 | 0.78 | CTSK (0.41) | CTSKCTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973037-B2 | Cathepsin cysteine protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2011-07-05 | — | — | US | disclosed |