Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 8/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA7 | P43166 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21573584 | 0.94 | ADRB2 (0.51) | ADRB2CHRM3OPRD1OPRK1NPC1 | |
| SCHEMBL21573506 | 0.79 | ADRB2 (0.65) | ADRB2CHRM3ADRB1 | |
| SCHEMBL24404603 | 0.72 | ADRB2 (0.47) | ADRB2CHRM3 | |
| SCHEMBL21568607 | 0.71 | ADRB2 (0.70) | ADRB2CHRM3ADRB1 | |
| SCHEMBL21568610 | 0.71 | ADRB2 (0.70) | ADRB2CHRM3ADRB1 | |
| SCHEMBL21573579 | 0.70 | ADRB2 (0.61) | ADRB2CHRM3ADRB1 | |
| SCHEMBL21573556 | 0.68 | ADRB2 (0.41) | ADRB2ADRB1DRD2ADRA1D | |
| SCHEMBL28338839 | 0.66 | ADRB2 (0.91) | ADRB2CHRM3 | |
| SCHEMBL18260006 | 0.66 | ADRB2 (0.91) | ADRB2CHRM3 | |
| SCHEMBL21568572 | 0.65 | ADRB2 (0.79) | ADRB2CHRM3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303333-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2019-11-20 | — | — | EP | disclosed |