Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 15/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 8/20 | 0.41 |
| ▸ | DRD2 | P14416 | 7/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20373416 | 0.77 | ADRB2 (0.40) | ADRB2ADRB1DRD2DRD3 | |
| SCHEMBL21573521 | 0.68 | KDM4E (0.37) | ADRB2ADRB1ADRA1DDRD2 | |
| SCHEMBL18946397 | 0.68 | ADRB1 (0.43) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL23223709 | 0.67 | ADRB2 (0.39) | ADRB2ADRB1 | |
| SCHEMBL14036266 | 0.67 | KDM4E (0.47) | ADRB2ADRB1DRD2 | |
| SCHEMBL19903846 | 0.67 | ADRB2 (0.36) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL21517469 | 0.63 | MEN1 (0.41) | ADRB2ADRB1DRD2DRD3ADRB3 | |
| Hydrochloric Acid SCHEMBL11692252 | 0.63 | ADRB2 (0.48) | ADRB2ADRB1DRD3ADRB3 | |
| SCHEMBL30254965 | 0.61 | ADRB2 (0.77) | ADRB2ADRB1DRD2DRD3ADRB3 | |
| SCHEMBL14260754 | 0.61 | ADRB2 (0.77) | ADRB2ADRB1DRD2DRD3ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303333-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2019-11-20 | — | — | EP | disclosed |