Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 4/20 | 0.50 |
| ▸ | ADH1A | P07327 | 4/20 | 0.50 |
| ▸ | ADH7 | P40394 | 3/20 | 0.50 |
| ▸ | ADH1C | P00326 | 3/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | ADH4 | P08319 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826230 | 0.77 | ADH1B (0.57) | ADH1BADH1AADH7ADH1CEPHX1 | |
| SCHEMBL2853062 | 0.77 | TSHR (0.44) | EPHX1 | |
| SCHEMBL2847082 | 0.75 | TSHR (0.44) | EPHX1 | |
| SCHEMBL9322927 | 0.74 | ADH1B (0.62) | ADH1BADH1AADH7ADH1CEPHX1 | |
| SCHEMBL13694800 | 0.74 | ADH1B (0.48) | ADH1BADH1AADH7ADH1CEPHX1 | |
| SCHEMBL1120398 | 0.74 | EPHX1 (0.39) | EPHX1 | |
| SCHEMBL6756345 | 0.72 | — | — | |
| SCHEMBL7753817 | 0.72 | THRB (0.44) | EPHX1 | |
| SCHEMBL6227646 | 0.72 | THRB (0.44) | EPHX1 | |
| SCHEMBL271073 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383867-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2021-04-14 | — | — | EP | disclosed |
| EP-3303333-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2019-11-20 | — | — | EP | disclosed |