Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.31 |
| ▸ | FLT4 | P35916 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20321544 | 0.83 | EGFR (0.41) | EGFR | |
| SCHEMBL21573743 | 0.81 | EGFR (0.42) | EGFR | |
| SCHEMBL21784550 | 0.78 | EGFR (0.44) | EGFRLMNAKMT2A | |
| SCHEMBL16282205 | 0.78 | EGFR (0.47) | EGFRHSP90AA1HSP90AB1TRPV4LIPE | |
| SCHEMBL5892464 | 0.78 | EGFR (0.47) | EGFRTRPV4LIPELMNAKMT2A | |
| SCHEMBL20209464 | 0.78 | HSP90AA1 (0.43) | EGFRHSP90AA1HSP90AB1TRPV4AMY1A | |
| SCHEMBL29695387 | 0.76 | EGFR (0.52) | EGFR | |
| SCHEMBL2112318 | 0.76 | EGFR (0.52) | EGFR | |
| SCHEMBL23772414 | 0.75 | EGFR (0.45) | EGFR | |
| SCHEMBL2355702 | 0.75 | LPL (0.40) | EGFRLIPEROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3569603-A1 | POLYCYCLIC COMPOUND, AND ORGANIC ELECTROLUMINESCENCE ELEMENT COMPRISING THE POLYCYCLIC COMPOUND | Idemitsu Kosan Co., Ltd. (JP) | 2019-11-20 | — | — | EP | disclosed |