SCHEMBL2355702

SCHEMBL2355702

CC1(C)OB(c2ccc(Cl)cc2F)OC1(C)C

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LPL P06858 5/20 0.40
LIPG Q9Y5X9 5/20 0.40
EGFR P00533 4/20 0.37
LIPE Q05469 1/20 0.34
JAK2 O60674 3/20 0.33
BTK Q06187 3/20 0.33
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
HTR2B P41595 1/20 0.31
ROCK1 Q13464 1/20 0.30
P2RX7 Q99572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29795220 1.00 LPL (0.40) LPLLIPGEGFRLIPEJAK2
SCHEMBL31554791 0.87 LPL (0.41) LPLLIPGEGFRLIPEJAK2
SCHEMBL18113006 0.87 LPL (0.41) LPLLIPGEGFRLIPEJAK2
SCHEMBL897058 0.81 LPL (0.50) LPLLIPGEGFRJAK2BTK
SCHEMBL29424567 0.81 LPL (0.50) LPLLIPGEGFRJAK2BTK
SCHEMBL15071862 0.81 TSHR (0.39) LPLLIPGEGFRJAK2BTK
SCHEMBL21042445 0.81 LIPG (0.50) LPLLIPGEGFRJAK2BTK
SCHEMBL37395635 0.80 LPL (0.41) LPLLIPGEGFRJAK2BTK
SCHEMBL6120636 0.80 LPL (0.41) LPLLIPGEGFRJAK2BTK
SCHEMBL17491867 0.80 LPL (0.53) LPLLIPGEGFRROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12628546-B2 Polymer and organic light-emitting diode using same LG CHEM, LTD. (KR) 2026-05-12 US disclosed
CN-116082355-B Anthracene compound, mixture, composition and organic electronic device 广州华睿光电材料有限公司 2025-05-16 CN disclosed
CN-114761462-B Polymer and organic light emitting diode using the same 株式会社LG化学 2024-02-23 CN disclosed
CN-114867703-B Fluorene-based compound, organic light-emitting device using the same, and method for manufacturing the same 株式会社LG化学 2024-01-12 CN disclosed
EP-4273146-A1 TRICYCLIC COMPOUND AND USE THEREOF Nanjing Zaiming Pharmaceutical Co., Ltd. (CN) 2023-11-08 EP disclosed
CN-116082355-A Anthracene compound, mixture, composition and organic electronic device 广州华睿光电材料有限公司 2023-05-09 CN disclosed
US-20230098935-A1 Fluorene-Based Compound, Organic Light-Emitting Device Using Same, And Manufacturing Method Therefor LG CHEM, LTD. (KR) 2023-03-30 US disclosed
US-20230087796-A1 Polymer and Organic Light-Emitting Diode Using Same LG CHEM, LTD. (KR) 2023-03-23 US disclosed
EP-4063427-A1 POLYMER AND ORGANIC LIGHT-EMITTING DIODE USING SAME LG Chem, Ltd. (KR) 2022-09-28 EP disclosed
EP-4063342-A1 FLUORENE-BASED COMPOUND, ORGANIC LIGHT-EMITTING DEVICE USING SAME, AND MANUFACTURING METHOD THEREFOR Lg Chem, Ltd. (KR) 2022-09-28 EP disclosed
CN-109293656-A Bcl-2 selective depressant and its preparation and use 北京赛林泰医药技术有限公司 2019-02-01 CN disclosed
WO-2018041248-A1 BCL-2 SELECTIVE INHIBITOR AND PREPARATION AND USE THEREOF 北京赛林泰医药技术有限公司 2018-03-08 WO disclosed
US-9340529-B2 Triazolones as fatty acid synthase inhibitors GLAXOSMITHKLINE LLC (US) 2016-05-17 US disclosed
US-8802864-B2 Triazolones as fatty acid synthase inhibitors GLAXOSMITHKLINE LLC (US) 2014-08-12 US disclosed
US-20140100213-A1 TRIAZOLONES AS FATTY ACID SYNTHASE INHIBITORS GLAXOSMITHKLINE LLC (US) 2014-04-10 US disclosed
EP-2538787-A1 TRIAZOLONES AS FATTY ACID SYNTHASE INHIBITORS GlaxoSmithKline LLC (US) 2013-01-02 EP disclosed
US-20120316151-A1 TRIAZOLONES AS FATTY ACID SYNTHASE INHIBITORS GLAXOSMITHKLINE LLC 2012-12-13 US disclosed
WO-2011103546-A1 TRIAZOLONES AS FATTY ACID SYNTHASE INHIBITORS GLAXOSMITHKLINE LLC (US) 2011-08-25 WO disclosed
US-6969716-B2 5-phenyl[1,2,4]triazines as ligands for GABA-A α2/α3 receptors for treating anxiety or depression MERCK SHARP & DOHME LTD. 2005-11-29 US disclosed
US-20040192692-A1 5-Phenyl[1,2,4]triazines as ligands for GABA-A alpha2/alpha3 receptors for treating anxiety or depression MERCK SHARP & DOHME, LTD. (GB) 2004-09-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12628546-B2 Polymer and organic light-emitting diode using same CCNE2, CCNL2, CCNB1 LPL 2662/4885LIPG 3605/4885EGFR 1776/4885
US-20230098935-A1 Fluorene-Based Compound, Organic Light-Emitting Device Using Same, And Manufacturing Method Therefor AFF1, FAR1, RFT1 LPL 2969/4885LIPG 4038/4885EGFR 1807/4885
US-20140100213-A1 TRIAZOLONES AS FATTY ACID SYNTHASE INHIBITORS FASN, FADS1, FADS2 LPL 270/4885LIPG 251/4885EGFR 1898/4885
US-20040192692-A1 5-Phenyl[1,2,4]triazines as ligands for GABA-A alpha2/alpha3 receptors for treating anxiety or depression GABRA1, GABRA5, GABRA2 LPL 4762/4885LIPG 4876/4885EGFR 715/4885
US-20120316151-A1 TRIAZOLONES AS FATTY ACID SYNTHASE INHIBITORS FASN, FADS1, FADS2 LPL 340/4885LIPG 247/4885EGFR 1979/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.