Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21574048 | 0.87 | GPBAR1 (0.36) | RXFP1PTPN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL16863570 | 0.85 | PDE4A (0.33) | RXFP1PTPN1NPC1ALDH1A1TP53 | |
| SCHEMBL16868801 | 0.83 | PDE4A (0.34) | RXFP1NPC1ALDH1A1TP53MAPT | |
| SCHEMBL29376079 | 0.81 | GPBAR1 (0.38) | RXFP1ALDH1A1MAPTSMN1; SMN2GPBAR1 | |
| SCHEMBL16150671 | 0.81 | GPBAR1 (0.38) | RXFP1ALDH1A1MAPTSMN1; SMN2GPBAR1 | |
| SCHEMBL16868757 | 0.79 | GPBAR1 (0.36) | RXFP1GPBAR1 | |
| SCHEMBL18354509 | 0.76 | PDE4A (0.32) | NPC1ALDH1A1MAPTMAPK1RAB9A | |
| SCHEMBL18354705 | 0.75 | MAPT (0.34) | RXFP1NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL18355933 | 0.74 | PDE4A (0.31) | NPC1ALDH1A1MAPTMAPK1RAB9A | |
| SCHEMBL24590303 | 0.74 | DHODH (0.33) | RXFP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3087053-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-11-20 | — | — | EP | disclosed |