Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 15/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16150671 | 0.92 | GPBAR1 (0.38) | GPBAR1RXFP1ALDH1A1MAPTHTT | |
| SCHEMBL29376079 | 0.92 | GPBAR1 (0.38) | GPBAR1RXFP1ALDH1A1MAPTHTT | |
| SCHEMBL16868757 | 0.89 | GPBAR1 (0.36) | GPBAR1RXFP1MLYCD | |
| SCHEMBL21574072 | 0.87 | RXFP1 (0.33) | GPBAR1RXFP1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL21574063 | 0.85 | GPBAR1 (0.36) | GPBAR1MLYCD | |
| SCHEMBL22332345 | 0.84 | GPBAR1 (0.38) | GPBAR1RXFP1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL18354632 | 0.83 | MLYCD (0.36) | GPBAR1RXFP1ALDH1A1MAPTHTT | |
| SCHEMBL14844306 | 0.83 | GPBAR1 (0.40) | GPBAR1RXFP1ALDH1A1MAPTHTT | |
| SCHEMBL18355489 | 0.82 | MLYCD (0.35) | GPBAR1ALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL16863570 | 0.82 | PDE4A (0.33) | GPBAR1RXFP1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3087053-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-11-20 | — | — | EP | disclosed |