Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5958188 | 0.91 | GRIA1 (0.49) | GRIA1GRIA2GRIA3KCNH2EGLN2 | |
| SCHEMBL13621591 | 0.85 | GRIA1 (0.46) | GRIA1GRIA2GRIA3KCNH2EGLN2 | |
| SCHEMBL11568772 | 0.83 | TSHR (0.52) | GRIA1GRIA2GRIA3HSD11B1MAOA | |
| SCHEMBL250894 | 0.83 | MAOA (0.50) | GRIA1GRIA2GRIA3KCNH2HRH3 | |
| SCHEMBL3706669 | 0.83 | KCNH2 (0.46) | GRIA1GRIA2GRIA3KCNH2HRH3 | |
| SCHEMBL23197880 | 0.82 | GRIA1 (0.43) | GRIA1GRIA2GRIA3KCNH2EGLN2 | |
| SCHEMBL20083485 | 0.82 | ESR2 (0.57) | GRIA1GRIA2GRIA3KCNH2EGLN2 | |
| SCHEMBL22816139 | 0.82 | ESR2 (0.59) | GRIA1GRIA2GRIA3KCNH2EGLN2 | |
| SCHEMBL11523793 | 0.82 | ALDH1A1 (0.64) | GRIA1GRIA2GRIA3KCNH2EGLN2 | |
| SCHEMBL7281867 | 0.82 | ESR2 (0.59) | GRIA1GRIA2GRIA3KCNH2EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2774968-B1 | OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE | JNC CORP (JP) | 2019-11-20 | — | — | EP | disclosed |