Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.48 |
| ▸ | PTAFR | P25105 | 11/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.44 |
| ▸ | EED | O75530 | 1/20 | 0.41 |
| ▸ | DCAF15 | Q66K64 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15573316 | 0.71 | CA1 (0.46) | HDAC8PTAFRHDAC5HDAC4CA1 | |
| SCHEMBL10822678 | 0.69 | HDAC8 (0.50) | HDAC8PTAFRDNMT1RAD52UHRF1 | |
| Hydrochloric Acid SCHEMBL3150169 | 0.69 | PTAFR (0.44) | HDAC8PTAFRDNMT1RAD52UHRF1 | |
| SCHEMBL1132663 | 0.66 | MYC (0.50) | CA1CA2CA7 | |
| SCHEMBL5599467 | 0.66 | CSNK2A2 (0.49) | — | |
| SCHEMBL2493946 | 0.65 | DNMT1 (0.62) | HDAC8PTAFRDNMT1RAD52UHRF1 | |
| SCHEMBL29381488 | 0.65 | DPP4 (0.56) | — | |
| SCHEMBL18622666 | 0.65 | SIGMAR1 (0.53) | DNMT1RAD52UHRF1CA1CA2 | |
| SCHEMBL8537937 | 0.65 | P2RX7 (0.45) | — | |
| SCHEMBL14344691 | 0.64 | PDCD1LG2 (0.45) | HDAC8PTAFRDNMT1RAD52UHRF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3333174-B1 | ANCILLARY LIGANDS FOR ORGANOMETALLIC COMPLEXES | UNIVERSAL DISPLAY CORP (US) | 2019-11-20 | — | — | EP | disclosed |