Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10594987 | 0.89 | DDB1 (0.48) | DDB1CRBNALOX15ALOX12CYP19A1 | |
| SCHEMBL21763866 | 0.83 | ACHE (0.45) | ALOX12CYP19A1ACHEALDH1A1 | |
| SCHEMBL15874726 | 0.82 | CYP19A1 (0.67) | DDB1CRBNALOX15ALOX12CYP19A1 | |
| SCHEMBL9144605 | 0.82 | CYP19A1 (0.67) | DDB1CRBNALOX15ALOX12CYP19A1 | |
| SCHEMBL6669546 | 0.82 | CYP24A1 (0.53) | DDB1CRBNALOX15ALOX12CYP19A1 | |
| SCHEMBL4422957 | 0.76 | ACHE (0.65) | ALOX15ALOX12CYP19A1MAOBACHE | |
| SCHEMBL10593732 | 0.75 | CYP24A1 (0.52) | DDB1CRBNCYP19A1MAOB | |
| SCHEMBL13885522 | 0.74 | CYP24A1 (0.48) | DDB1CRBNALOX15ALOX12CYP19A1 | |
| SCHEMBL15874767 | 0.74 | CYP24A1 (0.60) | CYP19A1MAOBALDH1A1 | |
| SCHEMBL4366122 | 0.74 | CYP24A1 (0.60) | CYP19A1MAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2585216-B1 | PI-ALLYLPALLADIUM AND PI-ALLYLNICKEL COMPLEXES FOR USE AS CATALYSTS IN CARBON-CARBON AND CARBON-NITROGEN COUPLING REACTIONS | JOHNSON MATTHEY PLC (GB) | 2019-11-20 | — | — | EP | disclosed |