Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.62 |
| ▸ | MAPK14 | Q16539 | 17/20 | 0.56 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.56 |
| ▸ | CSNK1E | P49674 | 3/20 | 0.56 |
| ▸ | MAPK13 | O15264 | 9/20 | 0.54 |
| ▸ | MAPK12 | P53778 | 9/20 | 0.54 |
| ▸ | MAPK11 | Q15759 | 9/20 | 0.54 |
| ▸ | RAF1 | P04049 | 7/20 | 0.54 |
| ▸ | BRAF | P15056 | 1/20 | 0.54 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.54 |
| ▸ | GCGR | P47871 | 1/20 | 0.54 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL155371 | 1.00 | ALOX5 (0.62) | ALOX5MAPK14CSNK1DCSNK1EMAPK13 | |
| SCHEMBL21068026 | 0.97 | ALOX5 (0.58) | ALOX5MAPK14CSNK1DCSNK1EMAPK13 | |
| SCHEMBL15606600 | 0.89 | MAPK14 (0.71) | MAPK14CSNK1DCSNK1EMAPK13MAPK12 | |
| SCHEMBL4565197 | 0.88 | MAPK14 (0.72) | ALOX5MAPK14CSNK1DCSNK1EMAPK13 | |
| SCHEMBL6447875 | 0.87 | MAPK13 (0.72) | ALOX5MAPK14CSNK1DMAPK13MAPK12 | |
| SCHEMBL4552055 | 0.86 | MAPK14 (0.76) | ALOX5MAPK14CSNK1DCSNK1EMAPK13 | |
| SCHEMBL6926311 | 0.85 | TEK (0.65) | ALOX5MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL7146991 | 0.82 | MAPK14 (0.80) | ALOX5MAPK14CSNK1DCSNK1EMAPK13 | |
| SCHEMBL6605306 | 0.81 | MAPK14 (0.68) | ALOX5MAPK14CSNK1DCSNK1EMAPK13 | |
| SCHEMBL6449407 | 0.81 | MAPK14 (0.77) | ALOX5MAPK14CSNK1DCSNK1EMAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3569636-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND A METHOD FOR THE PROPHYLAXIS AND TREATMENT OF THE ADHESION PROCESS | Joint Stock Company "Pharmasyntez" (RU) | 2019-11-20 | — | — | EP | disclosed |