Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 19/20 | 0.56 |
| ▸ | MAPK13 | O15264 | 15/20 | 0.56 |
| ▸ | MAPK12 | P53778 | 15/20 | 0.56 |
| ▸ | MAPK11 | Q15759 | 15/20 | 0.56 |
| ▸ | RAF1 | P04049 | 8/20 | 0.56 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.55 |
| ▸ | GCGR | P47871 | 6/20 | 0.52 |
| ▸ | BRAF | P15056 | 2/20 | 0.52 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.52 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.52 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL155371 | 0.97 | ALOX5 (0.62) | ALOX5MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL21574554 | 0.97 | ALOX5 (0.62) | ALOX5MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL6447875 | 0.88 | MAPK13 (0.72) | ALOX5MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL15606600 | 0.85 | MAPK14 (0.71) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL4565197 | 0.84 | MAPK14 (0.72) | ALOX5MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL4552055 | 0.83 | MAPK14 (0.76) | ALOX5MAPK14MAPK13MAPK12MAPK11 | |
| Sb-203580 SCHEMBL95208 | 0.82 | MAPK11 (0.75) | ALOX5MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL6469541 | 0.82 | MAPK14 (0.76) | ALOX5MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL6469294 | 0.82 | MAPK13 (0.76) | ALOX5MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL6467812 | 0.82 | MAPK14 (0.76) | ALOX5MAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |