SCHEMBL2157459

SCHEMBL2157459

CCN(CC(N)=O)c1ccc(N)c(C)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100B P04271 1/20 0.70
MAPT P10636 9/20 0.40
MAPK1 P28482 6/20 0.40
GFER P55789 5/20 0.40
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
ALOX15 P16050 2/20 0.40
SMN1; SMN2 Q16637 4/20 0.39
HTT P42858 4/20 0.39
LMNA P02545 3/20 0.39
CYP2C19 P33261 2/20 0.39
CYP1A2 P05177 1/20 0.39
HCRTR1 O43613 1/20 0.38
ALDH1A1 P00352 7/20 0.38
HPGD P15428 2/20 0.38
ATM Q13315 2/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
CYP3A4 P08684 3/20 0.38
TSHR P16473 2/20 0.38
TDP1 Q9NUW8 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9658445 0.88 S100B (0.70) S100BMAPTMAPK1GFERMEN1
Acetamide SCHEMBL10826862 0.87 S100B (0.80) S100BMAPTMAPK1GFERMEN1
SCHEMBL9197023 0.85 S100B (0.66) S100BMAPTMAPK1GFERMEN1
SCHEMBL9615469 0.83 S100B (0.79) S100BMAPTMAPK1GFERMEN1
SCHEMBL29350181 0.83 S100B (1.00) S100BMAPTMAPK1GFERMEN1
SCHEMBL34104 0.83 S100B (1.00) S100BMAPTMAPK1GFERMEN1
Hypochlorous Acid SCHEMBL6550511 0.82 S100B (0.89) S100BMAPTMAPK1GFERMEN1
Hydrochloric Acid SCHEMBL3385174 0.81 S100B (0.96) S100BMAPTMAPK1GFERMEN1
Hydrochloric Acid SCHEMBL2136137 0.81 S100B (0.96) S100BMAPTMAPK1GFERMEN1
SCHEMBL8006074 0.81 S100B (0.70) S100BMAPTMAPK1GFERMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0459900-B2 Process for dyeing of keratinic fibres with 2,4-diamino-1,3-dimethoxybenzene in an acid medium and composition using this process OREAL (FR) 2002-08-28 EP claimed
US-5900028-A Oxidation dye composition for keratin fibres comprising 2-amino-3-hydroxypyridine and a P-phenylenediamine or P-aminophenol oxidation base, and dyeing process L 'OREAL (FR) 1999-05-04 US claimed
US-5735909-A Compositions and processes for the oxidation dyeing of keratin fibres with an oxidation base, a meta-aminophenol coupler, and a 6-hydroxyindoline coupler L'OREAL (FR) 1998-04-07 US claimed
EP-0766958-B1 Oxidation dyeing composition for keratinous fibers comprising 2-amino-3-hydroxypyridine and an oxidation base and dyeing process OREAL (FR) 1997-11-19 EP claimed
EP-0605320-B1 Dye composition for keratinic fibres based on paraphenylenediamine, metaphenylenediamines and benzimidazol derivates, and the dyeing process using same OREAL (FR) 1997-04-09 EP claimed
EP-0728465-B1 Composition for dyeing keratinous fibers comprising a meta-aminophenol and 6-hydroxyindoline, and dyeing process using such a composition OREAL (FR) 1997-03-19 EP claimed
US-5578087-A Dyeing compositions for keratinous fibres based on para-phenylene-diamines, meta-phenylenediamine and benzimidazole derivatives, and dyeing process employing them L'OREAL (FR) 1996-11-26 US claimed
EP-0506549-B1 Dyeing composition for keratinous fibers containing oxidation dye precursors and hydroxybenzofurans as couplers and dyeing process making use of such a composition OREAL (FR) 1995-10-18 EP claimed
EP-0446132-B1 Keratinous fibres dyeing process with 6 or 7-monohydroxyindols at acidic pH and compositions OREAL (FR) 1994-09-14 EP claimed
EP-0459900-B1 Process for dyeing of keratinic fibres with 2,4-diamino-1,3-dimethoxybenzene in an acid medium and composition using this process OREAL (FR) 1994-01-05 EP claimed
EP-0416962-B1 KERATINOUS FIBERS DYEING PROCESS WITH INDOLE DYES AND OXIDATION DYE PRECURSORS AND DYEING AGENTS L'OREAL (FR) 1993-09-22 EP claimed
US-RE34300-E Hair dye L'OREAL (FR) 1993-07-06 US claimed
US-5203875-A Hair dyes also using ortho- and para-phenylenediamines or aminophenols; colorfastness; washfastness; perspiration resistance L'OREAL (FR) 1993-04-20 US claimed
US-5073174-A Hair, two stage, deep warm colors L'OREAL (FR) 1991-12-17 US claimed
EP-0295474-B1 CHLOROMETAPHENYLENEDIAMINES, THEIR USE AS COUPLING AGENTS IN OXYDATION COLOURING OF KERATINIC FIBRES, COLOURITY COMPOSITIONS FOR HAIR CONTAINING THESE COMPOUNDS AND COLOURING PROCESS USING THESE COMPOSITIONS L'OREAL (FR) 1991-07-17 EP claimed
US-4865619-A Use, as a coupler, of 2,4-diamino-1,3-dimethoxybenzene or one of its salts, in combination with oxidation dye precursors, for dyeing human hair, hair dyeing composition containing the said coupler and process for preparing the said coupler L'OREAL (FR) 1989-09-12 US claimed
US-4865618-A New chloro-meta-phenylenediamines, their use as couplers in the oxidation dyeing of keratinous fibres, dyeing compositions for hair containing these compounds and dyeing process using the said L'OREAL (FR) 1989-09-12 US claimed
US-4692166-A OXIDATION COLOR DYES USED WITH DIAMINOBENZENES OR AMINO PHENOLS; MINIMIZATION OF RED HUE L'OREAL (FR) 1987-09-08 US claimed
US-9929348-B2 Organic semiconductor composition comprising organic semiconductor material and polymer compound FUJIFILM CORPORATION (JP) 2018-03-27 US disclosed
US-4182886-A OPTICAL FILTERS IN COLOR PHOTOGRAPHY CIBA-GEIGY AKTIENGESELLSCHAFT (CH) 1980-01-08 US disclosed