Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | ANO1 | Q5XXA6 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20353902 | 0.89 | TP53 (0.56) | TP53ANO1MAPTTHRB | |
| SCHEMBL20340284 | 0.88 | ALDH1A1 (0.56) | TP53ANO1MAPTTHRB | |
| SCHEMBL24426894 | 0.86 | TP53 (0.51) | TP53ANO1MAPTTHRB | |
| SCHEMBL21577889 | 0.85 | ANO1 (0.61) | TP53ANO1MAPTTHRB | |
| SCHEMBL24426870 | 0.85 | MAPT (0.55) | TP53ANO1MAPTTHRB | |
| SCHEMBL21577816 | 0.76 | CNR2 (0.42) | MAPT | |
| SCHEMBL20354012 | 0.76 | CNR2 (0.57) | TP53MAPT | |
| SCHEMBL20340253 | 0.76 | ANO1 (0.59) | TP53ANO1MAPTTHRB | |
| SCHEMBL20353928 | 0.76 | ANO1 (0.59) | TP53ANO1MAPTTHRB | |
| SCHEMBL20353927 | 0.76 | ANO1 (0.59) | TP53ANO1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11279683-B2 | Thiophene derivatives as antiviral agents | ENYO PHARMA (FR) | 2022-03-22 | — | — | US | disclosed |
| US-20190352275-A1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | ENYO PHARMA (FR) | 2019-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11279683-B2 | Thiophene derivatives as antiviral agents | MAVS, EIF2AK2, IRF3 | TP53 2656/4885ANO1 4602/4885MAPT 4150/4885 |
| US-20190352275-A1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | MAVS, EIF2AK2, IRF3 | TP53 2656/4885ANO1 4602/4885MAPT 4150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.