Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.70 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.68 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.59 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.55 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308038 | 0.95 | LOXL2 (0.64) | LOXL2CYP4F2CYP4A11HIF1ASLC7A5 | |
| SCHEMBL14143797 | 0.92 | LOXL2 (0.64) | LOXL2CYP4F2CYP4A11HIF1ASLC7A5 | |
| SCHEMBL4767651 | 0.89 | HDAC1 (0.60) | LOXL2CYP4F2CYP4A11MRGPRX4ALDH1A1 | |
| SCHEMBL28206342 | 0.89 | CYP4F2 (0.68) | LOXL2CYP4F2CYP4A11HIF1ASLC7A5 | |
| SCHEMBL45633 | 0.88 | LOXL2 (0.68) | LOXL2CYP4F2CYP4A11HIF1ASLC7A5 | |
| SCHEMBL6566661 | 0.88 | LOXL2 (0.59) | LOXL2CYP4F2CYP4A11HIF1ASLC7A5 | |
| SCHEMBL1402945 | 0.86 | LOXL2 (0.71) | LOXL2CYP4F2CYP4A11HIF1ASLC7A5 | |
| SCHEMBL8246303 | 0.86 | LOXL2 (0.66) | LOXL2CYP4F2CYP4A11HIF1ASLC7A5 | |
| SCHEMBL21089603 | 0.86 | HIF1A (0.61) | LOXL2CYP4F2CYP4A11HIF1ASLC7A5 | |
| SCHEMBL9238872 | 0.86 | SMN1; SMN2 (0.59) | LOXL2CYP4F2CYP4A11HIF1ASLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190352459-A1 | Chemical Compounds For Coating Of Nanostructures | SPAGO NANOMEDICAL AB (SE) | 2019-11-21 | — | — | US | disclosed |