Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.70 |
| ▸ | HTR1D | P28221 | 2/20 | 0.70 |
| ▸ | HTR1B | P28222 | 2/20 | 0.70 |
| ▸ | HTR2C | P28335 | 2/20 | 0.70 |
| ▸ | HTR7 | P34969 | 2/20 | 0.70 |
| ▸ | HTR6 | P50406 | 2/20 | 0.70 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.70 |
| ▸ | HTR1A | P08908 | 1/20 | 0.70 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.70 |
| ▸ | HTR1E | P28566 | 1/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.70 |
| ▸ | HTR2B | P41595 | 1/20 | 0.70 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | APAF1 | O14727 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14513899 | 0.86 | HTR2A (0.70) | HTR2AHTR1DHTR1BHTR2CHTR7 | |
| SCHEMBL827572 | 0.85 | HTR2A (0.74) | HTR2AHTR1DHTR1BHTR2CHTR7 | |
| SCHEMBL28154603 | 0.84 | HTR2A (0.72) | HTR2AHTR1DHTR1BHTR2CHTR7 | |
| SCHEMBL28154602 | 0.84 | HTR2A (0.72) | HTR2AHTR1DHTR1BHTR2CHTR7 | |
| SCHEMBL14828735 | 0.83 | HTR2A (0.66) | HTR2AHTR1DHTR1BHTR2CHTR7 | |
| SCHEMBL17407615 | 0.83 | HTR2A (0.76) | HTR2AHTR1DHTR1BHTR2CHTR7 | |
| SCHEMBL13003112 | 0.83 | HTR2A (0.66) | HTR2AHTR1DHTR1BHTR2CHTR7 | |
| SCHEMBL707958 | 0.82 | HTR2A (0.70) | HTR2AHTR1DHTR1BHTR2CHTR7 | |
| SCHEMBL599674 | 0.82 | HTR2A (1.00) | HTR2AHTR1DHTR1BHTR2CHTR7 | |
| SCHEMBL5692300 | 0.82 | HTR2A (0.70) | HTR2AHTR1DHTR1BHTR2CHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11123304-B2 | Nanoparticles having poly(ester amide) polymer cores as drug delivery vehicles | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2021-09-21 | — | — | US | disclosed |
| US-20190350870-A1 | Particles as Delivery Systems | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11123304-B2 | Nanoparticles having poly(ester amide) polymer cores as drug delivery vehicles | ASGR1, F12, MSR1 | HTR2A 2589/4885HTR1D 3933/4885HTR1B 2975/4885 |
| US-20190350870-A1 | Particles as Delivery Systems | MTREX, APOB, HDLBP | HTR2A 2509/4885HTR1D 4496/4885HTR1B 3366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.