Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.69 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.65 |
| ▸ | MLLT1 | Q03111 | 9/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | MLLT3 | P42568 | 4/20 | 0.46 |
| ▸ | YEATS2 | Q9ULM3 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL173739 | 0.82 | NAMPT (1.00) | NAMPTHDAC1 | |
| SCHEMBL21580105 | 0.79 | NAMPT (0.59) | NAMPTHDAC1MLLT1MLLT3SMN1; SMN2 | |
| SCHEMBL21580117 | 0.77 | NAMPT (0.55) | NAMPTHDAC1MLLT1 | |
| SCHEMBL9416580 | 0.76 | HDAC6 (0.64) | HDAC1KDM1ASMN1; SMN2 | |
| SCHEMBL30147831 | 0.76 | NAMPT (0.52) | NAMPTHDAC1TBXAS1SMN1; SMN2 | |
| SCHEMBL31047579 | 0.74 | NAAA (0.56) | NAMPTHDAC1TBXAS1SMN1; SMN2L3MBTL1 | |
| SCHEMBL31047551 | 0.74 | NAAA (0.56) | NAMPTHDAC1TBXAS1SMN1; SMN2L3MBTL1 | |
| SCHEMBL4503327 | 0.72 | MMP13 (0.69) | ROCK2SMN1; SMN2L3MBTL1 | |
| SCHEMBL21580036 | 0.72 | NAMPT (0.52) | NAMPTHDAC1ROCK2 | |
| SCHEMBL29683753 | 0.71 | HDAC1 (0.48) | NAMPTHDAC1MLLT1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019218024-A1 | PAIN TREATING COMPOUNDS AND USES THEREOF | BIONOMICS LIMITED (AU) | 2019-11-21 | — | — | WO | disclosed |