⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13166786 | 1.00 | — | — | |
| SCHEMBL19320414 | 0.90 | NOD1 (0.35) | — | |
| SCHEMBL22844889 | 0.89 | — | — | |
| SCHEMBL25054510 | 0.87 | — | — | |
| SCHEMBL23764562 | 0.87 | — | — | |
| SCHEMBL21580587 | 0.87 | — | — | |
| SCHEMBL22316500 | 0.85 | FOLH1 (0.42) | — | |
| SCHEMBL16208441 | 0.85 | ALDH1A1 (0.33) | — | |
| SCHEMBL19483448 | 0.85 | FOLH1 (0.42) | — | |
| SCHEMBL18804751 | 0.85 | FOLH1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043833-B2 | Targeted compositions | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-07-23 | — | — | US | disclosed |
| US-20240216526-A1 | PREPARATION METHOD FOR DUAL-DRUG-LINKER OF ADC AND USE THEREOF | CHENGDU SCIMOUNT PHARMATECH CO., LTD. (CN) | 2024-07-04 | — | — | US | disclosed |
| US-20220168430-A1 | THERAPEUTIC METHODS FOR TREATING HEPATITIS B | ARBUTUS BIOPHARMA CORPORATION (US) | 2022-06-02 | — | — | US | disclosed |
| US-20210252018-A1 | Polyethylene Glycol-Conjugated Glucocorticoid Prodrugs and Compositions and Methods Thereof | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2021-08-19 | — | — | US | disclosed |
| US-10485809-B2 | Polyethylene glycol-conjugated glucocorticoid prodrugs and compositions and methods thereof | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2019-11-26 | — | — | US | disclosed |