Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21580697 | 0.85 | MRGPRX4 (0.40) | ARMRGPRX4PDGFRBPDGFRANPC1 | |
| SCHEMBL21581647 | 0.83 | DRD1 (0.42) | ARDRD1PDGFRBPDGFRANPC1 | |
| SCHEMBL14281622 | 0.83 | PDGFRB (0.54) | ARDRD1PDGFRBPDGFRANPC1 | |
| SCHEMBL21581644 | 0.81 | S1PR1 (0.44) | ARDRD1PDGFRBPDGFRANPC1 | |
| SCHEMBL21581583 | 0.79 | DYRK1A (0.44) | ARDRD1PDGFRBPDGFRANPC1 | |
| SCHEMBL21610244 | 0.77 | MRGPRX4 (0.40) | ARMRGPRX4MAPK10GAAMEN1 | |
| SCHEMBL21581601 | 0.77 | DRD1 (0.40) | DRD1NPC1RAB9ASCN10AKMT2A | |
| SCHEMBL7909509 | 0.74 | CA12 (0.56) | ARMRGPRX4SMN1; SMN2GAAMEN1 | |
| SCHEMBL12073737 | 0.74 | ACHE (0.56) | ARMRGPRX4MEN1ALDH1A1KMT2A | |
| SCHEMBL31193485 | 0.74 | CA12 (0.56) | ARMRGPRX4SMN1; SMN2GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019222816-A1 | SUBSTITUTED-PYRIDINYL COMPOUNDS AND USES THEREOF | BIONOMICS LIMITED (AU) | 2019-11-28 | — | — | WO | disclosed |