Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 3/20 | 0.40 |
| ▸ | KDR | P35968 | 3/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21580673 | 0.86 | DRD1 (0.35) | DRD1KDRBRAFHRH4RAF1 | |
| SCHEMBL21581644 | 0.82 | S1PR1 (0.44) | DRD1CRHR1NPC1RAB9AUHRF1 | |
| SCHEMBL17354613 | 0.81 | KDM4E (0.41) | GPR3SCN10ANPC1RAB9AKMT2A | |
| SCHEMBL21581580 | 0.79 | HAO1 (0.50) | DRD1CRHR1PPARGNPC1RAB9A | |
| SCHEMBL21581650 | 0.78 | DRD1 (0.44) | DRD1CRHR1PPARGKMT2AHAO1 | |
| SCHEMBL9918761 | 0.77 | AR (0.45) | GPR3SCN10AKMT2A | |
| SCHEMBL17354628 | 0.77 | RXRA (0.40) | DRD1GPR3RAB9AKMT2AHAO1 | |
| SCHEMBL21581648 | 0.77 | AR (0.43) | DRD1SCN10ANPC1RAB9AKMT2A | |
| SCHEMBL16289613 | 0.77 | UHRF1 (0.45) | DRD1GPR3CRHR1PTGS1PTGS2 | |
| SCHEMBL13719879 | 0.76 | KDM4E (0.58) | SCN10ARAB9AKMT2AHAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019222816-A1 | SUBSTITUTED-PYRIDINYL COMPOUNDS AND USES THEREOF | BIONOMICS LIMITED (AU) | 2019-11-28 | — | — | WO | disclosed |