SCHEMBL21582641

SCHEMBL21582641

CC1=Cc2cc([N+](=O)[O-])ccc2OC12C(C)c1ccccc1N2CCO

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.35
MEN1 O00255 4/20 0.35
KMT2A Q03164 4/20 0.35
SMN1; SMN2 Q16637 4/20 0.35
LMNA P02545 3/20 0.35
GAA P10253 2/20 0.35
RECQL P46063 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
PLIN1 O60240 1/20 0.35
THRB P10828 1/20 0.35
PKM P14618 1/20 0.35
TSHR P16473 1/20 0.35
PLIN5 Q00G26 1/20 0.35
ABHD5 Q8WTS1 1/20 0.35
POLB P06746 2/20 0.35
ATM Q13315 1/20 0.35
CHRM2 P08172 1/20 0.34
HTR1A P08908 1/20 0.34
ADRA2A P08913 1/20 0.34
DRD1 P21728 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8680042 0.89 CHRM2 (0.35) MAPTMEN1KMT2ACHRM2HTR1A
SCHEMBL22638053 0.78 DRD2 (0.33) MAPTMEN1KMT2ASMN1; SMN2LMNA
SCHEMBL22637431 0.78 MEN1 (0.32) MAPTMEN1KMT2ASMN1; SMN2LMNA
SCHEMBL22637479 0.76 MEN1 (0.30) MAPTMEN1KMT2ASMN1; SMN2LMNA
SCHEMBL8680236 0.75 HPRT1 (0.35) MAPTMEN1KMT2ASMN1; SMN2LMNA
SCHEMBL8680198 0.71 L3MBTL1 (0.42) MAPTMEN1KMT2ASMN1; SMN2RECQL
SCHEMBL2535787 0.71 MEN1 (0.41) MAPTMEN1KMT2ASMN1; SMN2TDP1
SCHEMBL8679963 0.70 MAPT (0.69) MAPTMEN1KMT2ASMN1; SMN2LMNA
SCHEMBL29894572 0.70 MAPT (0.69) MAPTMEN1KMT2ASMN1; SMN2LMNA
SCHEMBL30448229 0.70 MAPT (0.69) MAPTMEN1KMT2ASMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3846867-B1 A MEDICAL TUBULAR DEVICE BIOMODICS APS (DK) 2025-02-19 EP disclosed
EP-3846867-A1 A MEDICAL TUBULAR DEVICE Biomodics APS (DK) 2021-07-14 EP disclosed
CN-113038976-A Medical tubular device 比奥莫迪克斯有限公司 2021-06-25 CN disclosed
US-10506326-B2 Wearable devices with increased adhesion BOSE CORPORATION (US) 2019-12-10 US disclosed