SCHEMBL21583371

SCHEMBL21583371

Cc1cc(-c2cc(C)c(OC(=O)I)c(C)c2C)c(C)c(C)c1OC(=O)I

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.32
KDM4E B2RXH2 1/20 0.32
TP53 P04637 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
HSD17B10 Q99714 1/20 0.32
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9596191 0.82 HTT (0.47) HTTKDM4ETP53GAAMAPT
SCHEMBL14580035 0.76 POLB (0.44) HTTKDM4ETP53GAAMAPT
SCHEMBL21116923 0.76 THRB (0.37)
SCHEMBL23334735 0.73 KMT2A (0.44) KDM4EGAAMAPTHSD17B10POLB
SCHEMBL22048346 0.72 KMT2A (0.49) HTTKDM4EGAAMAPTPOLB
SCHEMBL12326160 0.69 ALDH1A1 (0.42) MAPTPOLB
SCHEMBL14580101 0.69 TSHR (0.43) KDM4EGAAMAPTPOLB
SCHEMBL23999958 0.68 HSD17B10 (0.41) KDM4EHSD17B10POLB
SCHEMBL22095998 0.67 SRC (0.32)
SCHEMBL2990084 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3575281-B1 DIAMINE COMPOUND, AND POLYIMIDE COMPOUND AND MOLDED ARTICLE IN WHICH SAID DIAMINE COMPOUND IS USED WINGO TECH CO LTD (JP) 2023-08-23 EP disclosed
EP-3575281-A1 DIAMINE COMPOUND, AND POLYIMIDE COMPOUND AND MOLDED ARTICLE IN WHICH SAID DIAMINE COMPOUND IS USED Wingo Technology Co., Ltd. (JP) 2019-12-04 EP disclosed