Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K12 | Q12852 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15723698 | 0.76 | CYP3A4 (0.37) | MAP3K12 | |
| SCHEMBL14015687 | 0.76 | ALDH1A1 (0.37) | MAP3K12 | |
| SCHEMBL18853941 | 0.76 | KDM4E (0.37) | MAP3K12 | |
| SCHEMBL21503677 | 0.74 | MAP3K12 (0.42) | MAP3K12 | |
| SCHEMBL15723703 | 0.73 | MAP3K12 (0.38) | MAP3K12 | |
| SCHEMBL15723827 | 0.73 | MAP3K12 (0.38) | MAP3K12 | |
| SCHEMBL18007558 | 0.73 | GABRP (0.38) | MAP3K12 | |
| SCHEMBL14401138 | 0.71 | MAP3K12 (0.35) | MAP3K12 | |
| SCHEMBL18007613 | 0.71 | MAP3K12 (0.33) | MAP3K12 | |
| SCHEMBL18007681 | 0.71 | MAP3K12 (0.35) | MAP3K12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3888749-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | The University of Queensland (AU) | 2021-10-06 | — | — | EP | disclosed |
| EP-3578547-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | The University of Queensland (AU) | 2019-12-11 | — | — | EP | disclosed |