Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21584410 | 0.90 | CYP1A2 (0.40) | KLKB1LMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1654721 | 0.75 | CYP1A2 (0.43) | LMNAALDH1A1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL21584392 | 0.75 | ABL1 (0.35) | MEP1BALDH1A1MAPTNPSR1 | |
| SCHEMBL21584408 | 0.74 | LMNA (0.43) | LMNAALDH1A1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL21584389 | 0.74 | CYP1A2 (0.36) | ALDH1A1MAPTNPSR1 | |
| SCHEMBL21584461 | 0.74 | KDM4E (0.40) | LMNAALDH1A1MAPTHTTRAB9A | |
| SCHEMBL1656975 | 0.74 | MEN1 (0.37) | MEP1BALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2682965 | 0.73 | SMN1; SMN2 (0.40) | LMNAMEP1BMAPTSMN1; SMN2 | |
| SCHEMBL1611059 | 0.73 | CRHR1 (0.39) | MEP1B | |
| SCHEMBL21584371 | 0.73 | PDE10A (0.35) | MEP1BALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019227771-A1 | SUBSTITUTED PYRIMIDINE-4-FORMIC ACID DERIVATIVE, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 (CN) | 2019-12-05 | — | — | WO | disclosed |