Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21584335 | 0.85 | MAPT (0.40) | TDP1MAPK1ALDH1A1POLBSLC6A2 | |
| SCHEMBL21584426 | 0.85 | MAPT (0.43) | TDP1ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL21584469 | 0.84 | MAPT (0.44) | TDP1MAPK1ALDH1A1KDM4EMAPT | |
| SCHEMBL21584431 | 0.84 | CASP3 (0.40) | TDP1ALDH1A1HSD17B10KDM4EMAPT | |
| SCHEMBL21584385 | 0.84 | MAPT (0.44) | TDP1ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL679235 | 0.83 | GRM6 (0.37) | MAPK1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL21584432 | 0.83 | TDP1 (0.46) | TDP1MAPK1ALDH1A1LMNAPOLB | |
| SCHEMBL29443551 | 0.83 | TDP1 (0.46) | TDP1MAPK1ALDH1A1LMNAPOLB | |
| SCHEMBL21584435 | 0.83 | MAPT (0.37) | ALDH1A1LMNAPOLBKDM4EMAPT | |
| SCHEMBL21584429 | 0.83 | MAPT (0.41) | TDP1MAPK1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019227771-A1 | SUBSTITUTED PYRIMIDINE-4-FORMIC ACID DERIVATIVE, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 (CN) | 2019-12-05 | — | — | WO | disclosed |