Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN1 | Q92952 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL2035112 | 0.86 | ACHE (0.43) | ACHEMEN1KMT2AALDH1A1KDM4E | |
| Acetic Acid SCHEMBL7069803 | 0.86 | ACHE (0.43) | ACHEMEN1KMT2AALDH1A1KDM4E | |
| Acetic Acid SCHEMBL2036516 | 0.83 | KMT2A (0.41) | ACHEMEN1KMT2AALDH1A1KDM4E | |
| Succinic Acid SCHEMBL2036515 | 0.81 | MEN1 (0.43) | ACHEMEN1KMT2AALDH1A1KDM4E | |
| Trifluoroacetic Acid SCHEMBL2158070 | 0.81 | KCNN1 (0.40) | KCNN1MEN1KMT2AALDH1A1KDM4E | |
| Trifluoromethanesulfonic Acid SCHEMBL7077338 | 0.80 | GPR3 (0.41) | ACHEALDH1A1KDM4EHPGD | |
| Trifluoromethanesulfonic Acid SCHEMBL31683143 | 0.80 | GPR3 (0.41) | ACHEALDH1A1KDM4EHPGD | |
| SCHEMBL29752612 | 0.80 | ACHE (0.53) | ACHE | |
| SCHEMBL307903 | 0.80 | ACHE (0.53) | ACHE | |
| Trifluoroacetic Acid SCHEMBL2072121 | 0.80 | MEN1 (0.42) | KCNN1MEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110183974-A1 | 1,2,4-OXADIAZOLE SUBSTITUTED PIPERIDINE AND PIPERAZINE DERIVATIVES AS SMO ANTAGONISTS | INSTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI (IT) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110183974-A1 | 1,2,4-OXADIAZOLE SUBSTITUTED PIPERIDINE AND PIPERAZINE DERIVATIVES AS SMO ANTAGONISTS | SHH, SMO, GLI1 | KCNN1 3482/4885ACHE 3931/4885MEN1 227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.