⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6231816 | 0.88 | — | — | |
| SCHEMBL351538 | 0.85 | ADRA2A (0.34) | — | |
| SCHEMBL6244828 | 0.85 | — | — | |
| SCHEMBL351887 | 0.80 | ADRA2A (0.32) | — | |
| SCHEMBL5108997 | 0.80 | — | — | |
| SCHEMBL976195 | 0.80 | — | — | |
| SCHEMBL353044 | 0.80 | ADRA2A (0.32) | — | |
| SCHEMBL9219543 | 0.78 | ADRA2A (0.31) | — | |
| SCHEMBL471908 | 0.78 | ADRA2A (0.32) | — | |
| SCHEMBL10410293 | 0.78 | ADRA2A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 830 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240075150-A1 | CONJUGATES COMPRISING REVERSIBLE LINKERS AND USES THEREOF | ASCENDIS PHARMA A/S (DK) | 2024-03-07 | — | — | US | claimed |
| CN-117355337-A | Protein-macromolecule conjugates and methods of use thereof | 奥迪曼药业科技有限公司 | 2024-01-05 | — | — | CN | claimed |
| US-11779681-B2 | Macroscopically alignable, injectable, soft hydrogel composition | DWI—LEIBNIZ-INSTITUT FÜR INTERAKTIVE MATERIALIEN E.V. (DE) | 2023-10-10 | — | — | US | claimed |
| EP-4218795-A2 | PTH COMPOUNDS WITH LOW PEAK-TO-TROUGH RATIOS | Ascendis Pharma Bone Diseases A/S (DK) | 2023-08-02 | — | — | EP | claimed |
| EP-4192508-A1 | CONJUGATES COMPRISING REVERSIBLE LINKERS AND USES THEREOF | Ascendis Pharma A/S (DK) | 2023-06-14 | — | — | EP | claimed |
| US-20230110994-A1 | CONJUGATES UNDERGOING INTRAMOLECULAR REARRANGEMENTS | ASCENDIS PHARMA A/S (DK) | 2023-04-13 | — | — | US | claimed |
| US-20230065814-A1 | CONJUGATES OF-ELECTRON-PAIR-DONATING HETEROAROMATIC NITROGEN-COMPRISING COMPOUNDS | ASCENDIS PHARMA A/S (DK) | 2023-03-02 | — | — | US | claimed |
| EP-4084872-A1 | CONJUGATES UNDERGOING INTRAMOLECULAR REARRANGEMENTS | Ascendis Pharma A/S (DK) | 2022-11-09 | — | — | EP | claimed |
| EP-3693031-B1 | MACROSCOPICALLY ALIGNABLE, INJECTABLE, SOFT HYDROGEL COMPOSITION | DWI LEIBNIZ INSTITUT FUER INTERAKTIVE MAT E V (DE) | 2022-11-02 | — | — | EP | claimed |
| CN-115175738-A | Conjugates undergoing intramolecular rearrangement | 阿森迪斯药物股份有限公司 | 2022-10-11 | — | — | CN | claimed |
| EP-0907668-A1 | AMPHIPHILIC, SEGMENTED COPOLYMER OF CONTROLLED MORPHOLOGY AND OPHTHALMIC DEVICES INCLUDING CONTACT LENSES MADE THEREFROM | Novartis AG (CH) | 1999-04-14 | — | — | EP | claimed |
| US-5807944-A | Amphiphilic, segmented copolymer of controlled morphology and ophthalmic devices including contact lenses made therefrom | CIBA VISION CORPORATION (US) | 1998-09-15 | — | — | US | claimed |
| WO-1997049740-A9 | AMPHIPHILIC, SEGMENTED COPOLYMER OF CONTROLLED MORPHOLOGY AND OPHTHALMIC DEVICES INCLUDING CONTACT LENSES MADE THEREFROM | — | 1998-04-30 | — | — | WO | claimed |
| EP-0688207-B1 | LIPID-POLYMER CONJUGATES AND LIPOSOMES | SEQUUS PHARM INC (US) | 1998-01-28 | — | — | EP | claimed |
| WO-1997049740-A1 | AMPHIPHILIC, SEGMENTED COPOLYMER OF CONTROLLED MORPHOLOGY AND OPHTHALMIC DEVICES INCLUDING CONTACT LENSES MADE THEREFROM | NOVARTIS AG (CH) | 1997-12-31 | — | — | WO | claimed |
| US-5631018-A | Lipid-polymer conjugates and liposomes | SEQUUS PHARMACEUTICALS, INC. (US) | 1997-05-20 | — | — | US | claimed |
| EP-0688207-A1 | LIPID-POLYMER CONJUGATES AND LIPOSOMES | SEQUUS PHARMACEUTICALS, INC. (US) | 1995-12-27 | — | — | EP | claimed |
| WO-1994020073-A1 | LIPID-POLYMER CONJUGATES AND LIPOSOMES | LIPOSOME TECHNOLOGY, INC. (US) | 1994-09-15 | — | — | WO | claimed |
| US-4916195-A | SULFO-ESTERIFICATION, RING-OPENING POLYMERIZATION | SHINETSU CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-10 | — | — | US | claimed |
| EP-0290109-A2 | Poly (N-acylethyleneimine)grafted polysiloxane and its preparation | Nippon Paint Co., Ltd. (JP) | 1988-11-09 | — | — | EP | claimed |