⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5108997 | 1.00 | — | — | |
| SCHEMBL215851 | 0.80 | — | — | |
| Alcohol SCHEMBL28228159 | 0.78 | ADRA2A (0.30) | — | |
| SCHEMBL329002 | 0.78 | ADRA2A (0.34) | — | |
| SCHEMBL351538 | 0.78 | ADRA2A (0.34) | — | |
| SCHEMBL6244828 | 0.75 | — | — | |
| SCHEMBL7933464 | 0.75 | — | — | |
| SCHEMBL7912667 | 0.75 | — | — | |
| SCHEMBL11687684 | 0.75 | — | — | |
| SCHEMBL14917574 | 0.74 | ADRA2A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116715699-A | Oxazoline chiral N, P ligand, preparation method and application thereof | 无锡学院 | 2023-09-08 | — | — | CN | claimed |
| US-10968343-B2 | Formaldehyde-free curable formulation | ROHM AND HAAS COMPANY (US) | 2021-04-06 | — | — | US | claimed |
| EP-2814489-A1 | COMPOSITIONS AND METHODS FOR THE MODULATION OF SPECIFIC AMIDASES FOR N-ACYLETHANOLAMINES FOR USE IN THE THERAPY OF INFLAMMATORY DISEASES | Epitech Group S.r.l. (IT) | 2014-12-24 | — | — | EP | claimed |
| WO-2013121449-A1 | COMPOSITIONS AND METHODS FOR THE MODULATION OF SPECIFIC AMIDASES FOR N-ACYLETHANOLAMINES FOR USE IN THE THERAPY OF INFLAMMATORY DISEASES | EPITECH GROUP S.R.L. (IT) | 2013-08-22 | — | — | WO | claimed |
| EP-1951686-B1 | QUINAZOLINE DERIVATIVES AS A MULTIPLEX INHIBITOR AND METHOD FOR THE PREPARATION THEREOF | HANMI PHARM IND CO LTD (KR) | 2013-04-03 | — | — | EP | claimed |
| US-20080318950-A1 | Quinazoline Derivatives as a Multiplex Inhibitor and Method For the Preparation Thereof | HANMI PHARM. CO., LTD (KR) | 2008-12-25 | — | — | US | claimed |
| EP-1951686-A1 | QUINAZOLINE DERIVATIVES AS A MULTIPLEX INHIBITOR AND METHOD FOR THE PREPARATION THEREOF | Hanmi Pharm. Co., Ltd. (KR) | 2008-08-06 | — | — | EP | claimed |
| WO-2007055514-A1 | QUINAZOLINE DERIVATIVES AS A MULTIPLEX INHIBITOR AND METHOD FOR THE PREPARATION THEREOF | HANMI PHARM. CO., LTD. (KR) | 2007-05-18 | — | — | WO | claimed |
| US-20020193361-A1 | Epothilone derivatives and methods for making and using the same | KOSAN BIOSCIENCES, INC. | 2002-12-19 | — | — | US | claimed |
| US-6489314-B1 | DUE TO THE INCREASING INTEREST IN EPOTHILONES AS ANTI-CANCER AGENTS, NOVEL DERIVATIVES OF THESE COMPOUNDS ARE NEEDED AND DESIRED TO MORE FULLY DEVELOP THEIR THERAPEUTIC POTENTIAL | KOSAN BIOSCIENCES, INC. | 2002-12-03 | — | — | US | claimed |
| EP-0907668-B1 | AMPHIPHILIC, SEGMENTED COPOLYMER OF CONTROLLED MORPHOLOGY AND OPHTHALMIC DEVICES INCLUDING CONTACT LENSES MADE THEREFROM | NOVARTIS AG (CH) | 2001-09-19 | — | — | EP | claimed |
| CN-1223673-A | Amphiphilic, segmented copolymer of controlled morphology and ophthalmic devices including contact lenses made therefrom | NOVARTIS AG (CH) | 1999-07-21 | — | — | CN | claimed |
| EP-0907668-A1 | AMPHIPHILIC, SEGMENTED COPOLYMER OF CONTROLLED MORPHOLOGY AND OPHTHALMIC DEVICES INCLUDING CONTACT LENSES MADE THEREFROM | Novartis AG (CH) | 1999-04-14 | — | — | EP | claimed |
| US-5807944-A | Amphiphilic, segmented copolymer of controlled morphology and ophthalmic devices including contact lenses made therefrom | CIBA VISION CORPORATION (US) | 1998-09-15 | — | — | US | claimed |
| WO-1997049740-A9 | AMPHIPHILIC, SEGMENTED COPOLYMER OF CONTROLLED MORPHOLOGY AND OPHTHALMIC DEVICES INCLUDING CONTACT LENSES MADE THEREFROM | — | 1998-04-30 | — | — | WO | claimed |
| WO-1997049740-A1 | AMPHIPHILIC, SEGMENTED COPOLYMER OF CONTROLLED MORPHOLOGY AND OPHTHALMIC DEVICES INCLUDING CONTACT LENSES MADE THEREFROM | NOVARTIS AG (CH) | 1997-12-31 | — | — | WO | claimed |
| US-4853050-A | Oil-in-water explosive composition containing asphalt | ICI AUSTRALIAN OPERATORS PTY LTD. (AU) | 1989-08-01 | — | — | US | claimed |
| EP-0067520-A2 | An emulsion explosive and a method of making and stabilising such explosive | AECI LIMITED (ZA) | 1982-12-22 | — | — | EP | claimed |
| CN-116715699-A | Oxazoline chiral N, P ligand, preparation method and application thereof | 无锡学院 | 2023-09-08 | — | — | CN | disclosed |
| EP-0008507-A1 | Derivatives of 2-oxazolines as antioxidants and compositions thereof | UNIROYAL, INC. (US) | 1980-03-05 | — | — | EP | disclosed |